The hotel boasts 468 spaciously furnished guestrooms, of which 18 are suites including the exclusive Executive Nikko Club Floor specially created for the comfort of business travellers. It is also renowned for its extensive meeting and convention facilities, all of which are centrally located on Level 2 of the Hotel. Further facilities include 24-hour reception, lift access, currency exchange facilities, hotel safe, air-conditioned restaurant, pub, wireless Internet access, hairdressing salon and parking. Room service is also available. The lobby is cavernous with 3 storey high ceiling and huge pillars. Grand staircases lead up to the mezzanine floors. Light marble floors and walls gives it an open feel.

A 90-minute drive from Kuala Lumpur International Airport, this business hotel is conveniently located along the prestigious Jalan Ampang, the heart of KL's business, shopping and entertainment district. It is only a heartbeat away from Kuala Lumpur City Centre, boasting 2 of the world's tallest buildings. Best of all, it is easily accessible through major road networks and the Ampang Park light rail LRT Station is right at the hotel's doorstep, with the city's Chinatown 15 minutes away.

Café Serena Brasserie is a tropical and friendly café with 168 seats offering a variety of international and local favourites every day alongside a fine view of the lobby waterfall. Buffets are served here for breakfast, lunch and dinner. High tea is also available at weekends. Authentic Japanese cuisine can be found in the Benkay Japanese Restaurant while fine Cantonese and Sichuan specialities are served in the Toh Lee Chinese Restaurant alongside international cuisine.